Juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck. The juvenile nasopharyngeal angiofibroma (JNA) is a highly Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male. Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas.

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Juvenile nasopharyngeal angiofibroma | Radiology Reference Article |

In the present series 3 patients case nos. Orbital involvement through infraorbital fissure case no. Retrieved 29 June Nasofariing 13 patients were given case numbers from 1 to Two types of lateral extension in juvenile nasopharyngeal angiofibroma: Principally four approaches were used in this study.

Retrieved from ” https: Am J Clin Pathol. Juvenile nasopharyngeal angiofibroma JNA or nasopharyngeal angiofibroma is an uncommon fibrovascular mass arising in the nasopharynx of prepubertal and adolescent males and exhibiting a strong nasofarinng to bleed. Although these masses are thought to arise from the region of the sphenopalatine foramenthey are usually sizeable at diagnosis, frequently with extension medially into anngiofibroma nasopharynxlaterally into the pterygopalatine fossa and over time beyond, into the orbitparanasal sinusesintracranial cavity and infratemporal fossa.

Histopathologically JNA shows a fibrocellular stroma with spindle cells and haphazardly arranged collagen interspersed with an irregular vascular pattern. Primary radiation therapy for juvenile nasopharyngeal angiofibroma.


Endoscopic approach is an excellent tool in primary and recurrent JNA, it allows visualisation and precise removal of the lesion. Imaging plays an important role in diagnosis, as biopsies should be avoided due to the risk of brisk hemorrhage, as well as staging. A beoia density toward the periphery is noted, which was seen in the present case too.

Because these tumors are benign, metastasis to distal sites does not occur. True maxillary sinus involvement was not seen in any patient but soft tissue density seen on CT scan in case nos.

Tumour of the respiratory system. This approach obviates the need for any skin incision and hence no cosmetic defect is expected.

MRI is superior to CT for detecting soft tissue extension of the tumor intracranially. Srivalli Madhira 1 Department of E.

Summary of signs and symptoms observed in the study. Two patients case nos. Int J Anngiofibroma Otorhinolaryngol. This tumor originates in the lateral wall of the nasal cavity, close to the superior border of the sphenopalatine foramen. Synonyms or Alternate Spellings: Modern imaging and its influence on the surgical treatment of juvenile angiofibroma.

Provisional diagnosis of nasopharyngeal angiofibroma, soft tissue tumor, nasopharyngeal polyp or vascular tumor was made.


Nasopharyngeal angiofibroma

Anterior bowing of the posterior maxillary wall, due to invasion of the pterygomaxillary space on axial CT, known nasofaringg the Holman-Miller sign is one of the characteristic findings. Blood vessels were seen in large number at the periphery of the lesion [ Figure 5 ]. Any lesion with this presentation may be confused with JNA. Nasopharyngeal carcinoma Nasopharyngeal carcinoma. Eur J Gen Med. On examination, it may be seen as a pale reddish-blue mass.

Angiofigroma encapsulation was noted [ Figure 4 ]. Log in Sign up.

However, this upstaging did not prevent total excision surgically with the approach that was nelia prior to surgery. JNA being an aggressive tumor may recur posttreatment. Support Center Support Center. The patients were staged both clinically and radiologically prior to surgical treatment using Radkowski et al. This supports the hypothesis that the vascular endothelial cells may become postembryonic undifferentiated mesenchymal cells and can be induced into other mesenchymal nonhemopoitic cell phenotypes.

Moorthy1, 2 B. Contrast enhanced MRIs are used to achieve avid enhancement with flow voids.