Carcinoma Mucoepidermoide de Glândulas. Salivares Menores. Mucoepidermoid Carcinoma of Minor Salivary Glands. Paulo Tinoco*, José Carlos Oliveira. Carcinoma mucoepidermoide de glándulas salivales en Brasil: relación clinicopatológica. Article (PDF Available) in Revista cubana de estomatología 49( 1). Pages CARTA CIENTÍFICO-CLÍNICA. DOI: / Carcinoma mucoepidermoide de labio. Mucoepidermoid Carcinoma of the Lip.
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Post contrast CT showing uniform enhancement and orbital involvement.
Are you a health professional able to prescribe or dispense drugs? Histological features and prognosis of patients with mucoepidermoid carcinoma of the parotid gland.
There is invasion into mucoepidermoife right orbital cavity with extraconal fat infiltration; however, the inferior rectus muscle remains intact. Views Read Edit View history. It is predominant in females and presents as two entities: Although the significance of this cytoplasmic staining remains unknown, Cheng et al. Sometimes when surgery is not possible due to extent of disease or if a patient is too frail for surgery, or declines surgery, palliative radiotherapy may be helpful.
Low grade and oncocytic tumors. Tuttavia numerosi studi fanno riferimento a casi isolati in cui questo tipo carcjnoma tumore origina dal mascellare, dalla mandibola, dalla ghiandola mammaria e dal timo. MEC was prevalent in the female gender The disease-free interval for recurrences and metastases ranged from 22 to months and 22 to months, respectively.
Previous studies of c-erbB-2 expression in salivary gland carcinomas are sparse, comprise heterogeneous subtypes, and show contradictory results Locati et al. Mucoepidermoid carcinoma of the parotid gland: Complex epithelial Warthin’s tumor Thymoma Bartholin gland carcinoma. mucoeidermoide
Lobular carcinoma in situ Invasive lobular carcinoma. Only 5 cases of parotid MEC have carcinomx reported in the main excretory duct, where they can be easily confused with minor salivary glands of the oral mucosa or accessory parotid gland Giger et al.
Mucoepidermoid carcinoma of the tonsil: a very rare presentation.
R; Dempsey, R J. Carcinoma of the parotid and submandibular glands a study of survival in patients. Microscopically, most intraoral MEC were classified as low grade of maligancy 27cases – The Kaplan-Meier method was used to plot survival curves with the log rank test for analysis of cumulative survival rates.
Further studies in order to clarify this point are warranted. Different conclusions may be attributed to the varying techniques used, criteria applied to determine positive c-erbB-2 expression, the diversity of lesions and mucoepidermoiide limited number evaluated in some studies.
This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment.
The majority of MECs 27 cases were classified as low grade of malignancy. In situ intraductal carcinoma of the breast was used as a c-erbB-2 positive control and negative controls were obtained by the omission of the primary carcinona.
Low grade with background mucin, two types of cells with bland nuclear features squamoid with dense cytoplasm and glandular with vacuolated cytoplasm. In our series the results were similar with 21 Histopathologic grading of salivary gland neoplasms. Moreover, Gibbons et al.
Mucoepidermoid carcinoma – Wikipedia
Intraoral Mucoepidermoid Carcinoma of Salivary Glands: Cords, sheets and clusters of mucous, squamous, intermediate and clear cells Low to high grade, although even high mucpepidermoide tumors lack marked nuclear atypia, frequent mitotic figures or extensive necrosis Occasional focal sebaceous cells, goblet type cells, oncocytic change, inflammatory reaction to extravasated mucin or keratin No squamous cell carcinoma in situ Low grade: Sinonasal and maxillary tumors were not included in this study as intraoral salivary gland tumors since that in these locations mucoepidermoid carcinoma presents different origin rather than glandular Ellis et al.
There is a growing consensus that an aggressive surgical approach with adjuvant radiotherapy must always be considered for more advanced cases that present with a high histological grade, positive margins and cervical involvement.
Print Send to a friend Export reference Mendeley Statistics. Acrcinoma Carcinoma MEC is the most common malignancy of salivary gland tumors, occurring most frequently in the major salivary glands, predominantly the parotid gland Giger et al. Histopathologic image of mucoepidermoid carcinoma. Mucoepidermoid carcinoma can also be found in other organs, such as bronchilacrimal sac and thyroid gland.
Mucoepidermoid carcinoma in a year-old girl. Radiation Oncology London, England. After comparing the morphological features of MEC with other chronic inflammatory non-neoplastic lesions of the salivary glands it was theorized that these cells originated in the ductal system Foschini et al.
Mucoepidermoid carcinoma of the tonsil: a very rare presentation.
For highgrade tumors, surgery and radiotherapy is recommended. A year-old male patient presented with a growth of the right palatal region mycoepidermoide occurring over the last twenty years.
Immunoexpression of c-erbB-2 and p53 in benign and malignant salivary neoplasms with myoepithelial differentiation. This provides further support to the existence of distinct molecular mechanisms in salivary gland carcinogenesis associated with the overexpression of c-erbB In our series, patients demonstrated an earlier average age of occurrence, with a peak of incidence in the mucoepidermiide and fourth decades of life, whereas previous studies described a prevalence in fifth and sixth decades of life Auclair et al.
The high percentage of previously observed positive cases 21 cases, Small cell ,ucoepidermoide Combined small cell carcinoma Verrucous carcinoma Squamous cell carcinoma Basal cell carcinoma Transitional cell carcinoma Inverted papilloma.
MEC is reported to manifest variable biologic aggressiveness, basically showing correlation with its histological features and is graded by a 3-tiered system Auclair et al, This overexpression may be due to the process envolving histogenesis and celular differentiation.
The c-erbB-2 oncoprotein is involved in matrix degradation and proteolitic activity as well as in the increase in vessel permeability, endothelial cell growth, proliferation, migration, and differentiation Verbeek et al. This item has received.