con el diagnóstico histopatológico de cordoma de la base del cráneo .. magnética cerebral, corte sagital, secuencia T1, cordoma del clivus. Resección endoscópica de cordoma del clivus. Descripción de un chordoma; clivus; endoscopic resection; malignant tumor. RESUMEN. Download Citation on ResearchGate | On Dec 19, , Ines Gamboa and others published Resección endoscópica de cordoma del clivus. Descripción de un.

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Intradural Retroclival Chordoma

Photomicrographs of the tumor specimen. Her magnetic resonance images demonstrated an inhomogeneously contrast-enhanced large tumor growing into right cavernous sinus and Meckel’s cave located totally within intradural retroclival region. MRI of intracranial chordomas. Cells with cytoplasmic vacuoles and clear glycogen lakes arrows are present.

Views Read Edit View history. Traditionally, surgical resection has been the first line of treatment when feasible, with radiotherapy offered for recurrent cases. Sitting, especially driving, aggravated the pain, clivjs standing and lumbar hyperextension provided some ddel.

This herniation was not evident on the magnetic resonance imaging despite axial sections through this interspace. Laminectomy and discectomy with exploration of the epidural process were recommended. Although this tumor lends itself to complete removal, long-term follow-up monitoring is needed clius determine the possibility of recurrence.

F ratio of 2: Our experience suggests that at least some cranial chordomas enhance unpublished data. These foci were micro- rather than macroscopic, were entirely intraosseous, and dl no physical resemblance to ecchordosis physaliphora occurring in the cranial region.

Axial Gd-enhanced T1-weighted image. Preoperative hearing threshold was 90 dB on the right and 45 dB on the left side by brainstem auditory evoked potential BAEPand it was improved to 35 dB on the right and 30 dB on the left side by BAEP studied on 11th postoperative day.


Furthermore, unlike other chordomas, intradural chordomas are amenable to resection. A portion of the tumor with sheet-like growth of vacuolated cells. The radiological characteristics of the lesion were misleading as it mimicked an arachnoid cyst or a neurogenic neoplasm.

Examination On initial evaluation, the patient had ataxic gait. She underwent retromastoid suboccipital craniotomy to resect the tumor mass and adjuvant gamma knife radiosurgery for remnant tumor at 1 month after operation.

Also, proton-beam irradiation is reported to be efficacious for the treatment of chordomas The tumor appeared as a low-intensity area on the T1-weighted image and deel a high-intensity area on the T2-weighted image.

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Chordoma | Radiology Reference Article |

Find articles by Sun-Il Lee. The MIB-1 proliferating cell index may be useful in the histological differential diagnosis of chordomas, which are neoplastic tumors, and clrdoma, which are not true tumor The interest of this case lies not only in the nature and location of the incidentally discovered tumor but also in its radiological presentation as an asymptomatic lesion at one lumbar level associated with a symptomatic disc extrusion at another lumbar level.

At her follow-up examination 1 year later, the patient reported improvement of both back and thigh pain. Typically the mass projects posteriorly at midline, indenting the pons; this characteristic appearance has been termed the so-called thumb sign.

Histological findings The tumor tissue was histologically characterized by lobules composed of typical physaliphorous cells with abundantly vacuolated cytoplasm. Krayenbuhl H, Yasagil MG.

The proximity of chordomas to vital neurological structures such as the brain stem and nerves limits the dose of radiation that can safely be delivered. The patient was not aware of progressive neurological loss.


Cerebrospinal fluid fistula secondary to ecchordosis physaliphora. Recurrence, including seeding along the operative tract, is common. Benign bone erosion with sclerotic borders can be seen arrowindicating a long-standing erosive, rather than destructive, process. Some authors 14 reported that the surgically total excision was goal of treatment because the intradural chordomas had slower growth pattern and sharply circumscribed margins compared with classic chordomas.

Such tumors often showed extraosseous extensions that were out of proportion to the degree of osseous involvement and were most often anterior and lateral but did involve the posterior spinal area.

Extraosseous spinal chordoma

The decision whether complete or incomplete surgery should be performed primarily depends on the anatomical location of the tumor and its proximity to vital parts of the central nervous ocrdoma. They most commonly involve cervical particularly C2followed by lumbar, and then the thoracic spine. Support Radiopaedia and see fewer ads.

The initial lumbar pain, which developed after a prolonged period of sitting, was ddel for a number of hours then slowly moderated over 5 days without fully abating. Operation Under the impression of acoustic schwannoma, the patient underwent operation. True malignant forms of chordomas occasionally have areas of typical chordoma as well as undifferentiated areas, most often fibrosarcoma.

Primary intradural pontocerebellar chordoma metastasizing in the subarachnoid spinal canal. Additionally, it represents an example of intraspinal extraosseous chordoma, a lesion not previously described.

J Korean Neurosurg Soc.