Available online at CURCUMA CAESIA ROXB. AND IT’S MEDICINAL. USES: A REVIEW. Sonjit Das, ProdyutMondal and Md. Kamaruz Zaman*. PDF | On Apr 19, , Sonjit Das and others published CURCUMA CAESIA ROXB. AND IT’S MEDICINAL USES: A REVIEW. Black turmeric is known to have certain medicinal values. The curcumin content when I read certain papers, It was very low ~ %. Now I am wondering.

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Also it was aimed to evaluate the protective effect of C. Phytochemical investigation and evaluation of anthelmintic activity of Curcuma amada and Curcuma caesia: Each animal received distilled water Group 2: Study of caaesia anti-ulcerogenic activity of the ethanolic extracts of rhizome of Curcuma caesia eecc against gastrsic ulcers in experimental animals.

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Abstract The rhizomes of Curcuma caesia Roxb. The genotypes of the test strains were checked routinely for their histidine requirement, rfa mutatios, UV sensitivity uvrB mutation. The use of DPPH assay provides an easy and a rapid way to evaluate antioxidants by spectrophotometer [37]. Cellular system has developed many endogenous antioxidants such as superoxide dismutase SODcatalase, glutathione, glutathione peroxidases and reductase, and nonenzymatic antioxidants vurcuma vitamin E tocopherols and tocotrienolsvitamin C, etc.

Retrieved from ” caexia Banerjee A, Nigam SS.

These preventive agents can inhibit the mutation and cancer initiation process by modulating phase I and phase II enzymes, by blocking reactive species either by scavenging, electron donation or through chelation and thus maintains the DNA structure. Non enzymatic antioxidant defence systems. Therefore we have selected the rhizome of this plant and evaluated the antioxidant and antimutagenic activity of some of the selected extracts against indirectly acting mutagen cyclophosphamide.


Antioxidant and antimutagenic activity of Curcuma caesia Roxb. rhizome extracts

Literature reviews of Sarangthem and Haokip [41] also confirms that maximum curcuminoids, oil content, flavonoids, phenolics, different important amino acids, protein and high alkaloids are contained in the rhizome of this species. Considering the importance of natural products in modern phytomedicine, the antioxidant and antimutagenic activities of C.

Currently many of the Researchers is working under his guidance and many of them have awarded Ph. Antimutagenic activity of methanolic extract of Ganoderma lucidum and its effect on hepatic damage caused by benzo[ a curcmua.

Percentage inhibition was calculated using cjrcuma formula [29]. The inhibition mixture was calculated using the formula:. Leishangthem S, Dinendra SL. Recent advances in the chemoprevention of cancer.

Curcuma caesia

Biochem Biophys Res Commun. Orient Pharm Exp Med. Higher mutagenicity was found when CP was activated with S9 but inhibition of this microsomal activity was observed in the presence of rhizome extract.

Table 1 Preliminary phytochemical screening of methanolic extract of Curcuma caesia Roxb. World Cancer Report Antioxidant activity applying an improved ABTS radical cation decolorization assay. But their amount crucuma found to be reduced with the administration of the extract at different concentrations. Medicinal plants in the prevention and therapy of cancer.

This page was last edited on 6 Decemberat Treatment of cancer with chemotherapeutic drugs has been suggested to prevent cancer cells however they are often limited with their toxicity to normal cells. Thousand polychromatic erythrocytes PCEs were scored for each group of animals to determine the frequency of micronucleated polychromatic erythrocytes.


Critical Reviews in Food Science and Nutrition. Cyclophosphamide CP is a nitrogen mustard alkylating agent[ 6 ] used in various types of cancer chemotherapy, but the International Agency for Research Centre has identified it as a carcinogen for both animals and humans. All the drugs and chemicals used in this experiment were procured from Segma sales, Silchar, Assam, India, which were kindly provided by Himedia, India.

Antioxidants have been reported to act as scavengers of singlet oxygen and free radicals in biological systems [42][43]. Similar trend was followed for methanoilc extract of C. The quenching of free radical activity of different extracts were determined by spectrophotometric method against 2,2-diphenylpicryl hydrazyl DPPH following [25].

Lipid peroxidation in liver homogenates as index of activity.

Heisanam Pushparani DeviShe is a Research Scholar in the Department of Biotechnology, Assam University Silchar and her interest is on medicinal plant studies like antioxidant activity, antimutagenic activity, antigenotoxic cawsia etc. In-vitro evaluation of antioxidant activity of Curcuma caesia Roxb. In conclusion, the present study has shown for the first time that C. An increase in the number of micronuclei was observed when treated with CP only as shown in Table 4.

Curcuma caesia — Vikaspedia

Czesia assay for lipid peroxidation The assay was performed following[ 31 ] with slight modifications. Free Radic Biol Med. Cyclophosphamide induced lipid peroxidation and changes in cholesterol content: