Erythema elevatum diutinum (EED) is a rare, chronic dermatosis that is characterized by red–violet to red–brown papules, plaques, and. Erythema elevatum diutinum (EED) is a chronic form of leukocytoclastic vasculitis consisting of violaceous, red-brown, or yellowish papules. Erythema elevatum diutinum. Authoritative facts about the skin from DermNet New Zealand.

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Eritema elevatum diutinum as a differential diagnosis of rheumatic diseases: case report.

Please enter User Name. Erythema elevatum diuhinum – a case successfully treated with colchicine. The severity of EED does not, however, appear to be dependent on the total paraprotein levels. Typically, the lesions are asymptomatic, but there have been reports of patients who experienced pruritus and burning or tingling sensations, especially early in the disease course. Erythema elevatum diutinum complicated by rheumatoid arthritis.

Trunk is usually spared. The incidence of EED is unknown; however, it appears to be a rare disease. Antineutrophil cytoplasmic antibodies ANCA of elevatuum immunoglobulin G IgG type have proven eiutinum for the diagnosis and monitoring of disease activity in various systemic vasculitides, including granulomatosis with polyangiitis Wegener’smicroscopic polyangiitis MPOpolyarteritis nodosa, and Churg—Strauss syndrome.

PMC ] [ PubMed: Are you a health professional able to prescribe or dispense drugs? Simultaneous occurrence of two rare cutaneous markers of poor prognosis in myelodysplastic syndrome: EED has been described in association with a number of systemic diseases.


Erythema elevatum diutinum – Wikipedia

Initially, the lesions are erythematous and soft but with time become red—brown or violaceous in color and firm to palpation secondary to fibrosis. Subsequently, the lesions evolved with the formation of violet-colored erythematous papules that were confluent in plaques with a light brown surface Figure 1.

By using this site, you agree to the Terms of Use and Privacy Policy. We established treatment with dapsona and we discussed its evolution. To access free multiple choice questions on this topic, click here.

Sign in via Shibboleth. There was no history of streptococcal infection, hematological disorders or autoimmune disease.

Erythema elevatum diutinum

Evaluation A skin biopsy is the most useful study for the diagnosis of EED. Arthralgias may develop in underlying joints, but extracutaneous involvement is extremely rare. Previous treatment with topical corticosteroids had been unsuccessful. Most common sites of involvement are the extensor surfaces of the hands, fingers, elbows, knees, legs, and Achilles tendon.

Clear Turn Off Turn On. Click here for information on linking to our website or using our content or images. Immune complex deposition results in complement activation, neutrophilic infiltration, and the release of destructive enzymes. Late-stage nodular erythema elevatum diutinum.


It is relatively non-toxic and can be used in the treatment of neutrophil-driven disorders, with fewer side effects elevtaum dapsone. The first case had a history of rheumatic disease but the other patients were associated with hepatitis C infections and with elevated levels of Ig A.

On exam, lesions of EED present as red—brown, yellowish, or violaceous papules, plaques, or nodules. Vanessa Ngan, Staff Writer, Erythema elevatum diutinum is a chronic and rare dermatosis that is considered to be a variant of leukocytoclastic vasculitis. A chronic leukocytoclastic vasculitis typified by a distinctive clinical pattern. Erythema elevatum diutinum and IgA myeloma: Histologically, early lesions of erythema elevatum diutinum show leukocytoclastic vasculitis.

Accessed December 31, Please review our privacy policy. One month after diagnosing HIV infection, the patient presented a neurological condition of right-side motor impairment. Si es usted socio de AEDV: Today, one-and-a-half years after the HIV-positive blood test and the beginning of antiretroviral therapy, the patient has not had any recurrence of the skin lesions.