cómo se transporta la glucosa través de la membrana celular? diana díaz hernández, luis carlos burgos herrera de la célula para su ingreso requiere una. RESUMEN El transporte de la glucosa a través de la membrana plasmática de a sodio (SGLT) y los sistemas facilitadores del transporte de glucosa (GLUT). Se han descrito dos sistemas de transporte de glucosa y de otros monosacáridos : y los transportadores de glucosa llamados GLUT (glucosa transporters).

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Structure and function of hexose transporters. Membrane proteinscarrier proteins: Cloning and functional expresssion in bacteria of a novel glucose transporter present in liver, intestine, kidney, and B-pancreatic islet cells.

Glucose transporter – Wikipedia

Evidence for a family of human glucose transporter-like proteins. The key point here was ‘flux coupling’, the cotransport of sodium and glucose in the apical membrane of the small intestinal epithelial cell. Found in adipose tissues and striated muscle skeletal muscle and cardiac muscle. In Saccharomyces cerevisiae glucose transport takes place through facilitated diffusion. Reduced content and preserved translocation of glucose transporter GLUT 4 in white adipose tissue of obese mice.

Am J Nephrol ;4: Physiol Behav ; Pretranslational suppression of a glucose transporter protein causes insulin resistance in adipocytes from patients with non-insulin-dependent diabetes mellitus and obesity. Physiol Rev ; In Augustin Prague, Robert K.

Glucose transporter

Levels in cell membranes are increased by reduced glucose levels and decreased by increased glucose levels. Tese – Mestrado -Escola Paulista de Medicina.


Efeito do diabetes sobre os transportadores de glicose de epitelio renal. Transcription repressed by glucose.

Molecular biology of mammaliam glucose transporters.

Abundant during stationary phase, sporulation and low glucose conditions. How to cite this article. The function of these new glucose transporter isoforms is still not clearly defined at present. Braz J Med Biol Res ; Whether mechanisms exist to glucoosa cell-surface translocation of these transporters is not yet known, but it has clearly been established that insulin does not promote GLUT6 and GLUT8 cell-surface translocation.

Decreased glucose transporter GLUT 4 content in insulin-sensitive tissues of obese aurothioglucose- and monosodium glutamate-treated mice. Membrane Transport and Metabolism. Each glucose transporter isoform plays a specific tfansportadores in glucose metabolism determined by its pattern of tissue expression, substrate specificity, transport kinetics, and regulated expression in different physiological conditions.

Most non- autotrophic cells are unable to produce free glucose because they lack expression of glucosephosphatase and, thus, are involved only in glucose uptake and catabolism.

Regulation of glucose-transporter function. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease.

Transportadores de glucosa by Jose Rodriguez on Prezi

Comparison of kinetic parameters. Quantification of GLUT4 transporter in insulin-sensitive tissues from pinealectomized rats. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Diabetes Care ; Half a century later this idea has turned into one of the most studied of all transporter proteins SGLT1the sodium—glucose cotransporter.

Evidence for cytosolic sugar binding sites in erythrocytes”. Is expressed by renal tubular cells, liver cells and pancreatic beta cells.


Nature Lond ; This page was last edited on 24 Octoberat This hypothesis was rapidly tested, refined, and extended [to] encompass the active transport of a diverse range of molecules and ions into virtually every cell type.

The effect of adipose cell size on the measurement of GLUT 4 in white adipose tissue of obese mice.

Transportador de glucosa

J Clin Invest ; Molecular physiology of sodium-glucose cotransporters. Effect of the thermogenic agent BRL A. Proceedings of a Symposium held in Prague, August 22—27, All three monosaccharides glucosegalactoseand fructose are transported from the intestinal mucosal cell into the portal circulation by GLUT2.

It is also present in the basolateral membrane of the small intestine epithelium. Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose across the plasma membrane.

Structure and function of mammalian facultative sugar transporters. Is a high-frequency and low-affinity isoform. In the adult, it is expressed at highest levels in erythrocytes and also in the endothelial cells of barrier tissues such as the blood—brain barrier. Annu Rev Physiol ; American Journal of Physiology.

Molecular physiology of glucose transporters. GLUT is a type of uniporter transporter protein.

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