Kaposi’s varicelliform eruption is a rare and potentially fatal viral infection caused mainly by reactivation of herpes simplex virus. It concomitantly occurs with. Disseminated herpes or vaccinia in the setting of underlying skin diseases is known as Kaposi’s varicelliform eruption (KVE). Patients typically present with. It is autosomal dominant in transmission. Patients with DWD are prone to frequent superinfection including the rare complication of Kaposi varicelliform eruption.
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Unusual complication of vemurafenib treatment of metastatic melanoma: Vesiculopustules often evolve into crusted, hemorrhagic, and punched-out skin erosions that may enlarge and coalesce to form extensive denuded areas which are more likely to get a bacterial infection.
It is characterized by widespread clusters of umbilicated vesicopustules and eroded vesicles, alternating with punched-out ulcers covered by hematic crusts usually located over the head, neck, and trunk.
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The most serious ophthalmological sequela is herpetic keratitis which may lead to vision loss resulting from corneal scarring. Open in a separate window. The Tzanck smear, viral cultures, skin biopsy, or detection of viral DNA by Polymerase Chain Reaction may be helpful in doubtful cases. It occurs more frequently in children, probably due to its relationship with atopic dermatitis.
Viral cutaneous conditions, including viral exanthema B00—B09— Primary infection with Herpes Simplex 1 virus on previous atopic dermatitis eczema herpeticum. Views Read Edit View history. For outpatients the administration of oral valacyclovir had a higher bioavailability. N Am J Med Sci. Journal of the American Academy of Dermatology.
How to cite this article: Get free access to newly published articles. Eczema herpeticum eruptin first described by Austrian dermatologist Moriz Kaposi in This article has been cited by other articles in PMC.
Kaposi’s varicelliform eruption Shenoy MM, Suchitra U – Indian J Dermatol Venereol Leprol
Indian J Dermatol Venereol Leprol. The recurrent type occurs in adulthood and is usually a milder and more localized form, generally presenting without viremia.
Clear Turn Off Turn On. To access free multiple choice questions on this topic, click here. However, the finding of cytoplasmic inclusion bodies in histological examination suggested a viral origin. Sign in to make a comment Sign in to your personal account. Although rare, it is potentially life-threatening disorder. Purchase access Subscribe to the journal. The disease equally affects men and women and does not appear to have a specific ethnic predominance. Textbook of atopic dermatitis.
Kaposi’s varicelliform eruption: A case series
Create a free personal account to download free article PDFs, sign up for alerts, and more. History and Physical Patients with Kaposi varicelliform eruption present with a sudden skin eruption of painful clusters of umbilicated vesicles and pustules. Other viruses such as Coxsackie A 16, vaccinia,[ 1 ] and varicella zoster[ 2 ] have also been implicated in its pathogenesis.
Histopathology A skin biopsy is not required to confirm a diagnosis, but if it is performed, histological findings include intra-epidermal blister, acantholysis, multinuclear giant cells with intranuclear inclusion, and ballooning degeneration of the keratinocytes. J Am Acad Dermatol. The first ended fatally, and specialized animal laboratory studies or autopsy findings were nonobtainable.
It concomitantly occurs with preexisting skin conditions,[ 3 ] mostly atopic dermatitis ADwith a higher prevalence in childhood,[ 1 ] although it can occur at any kapoai.
Kaposi Varicelliform Eruption – StatPearls – NCBI Bookshelf
It is held that defective skin barrier acting in conjunction with immune deficiencies seems to lead to the development of the disease. PubMed Links to PubMed. J Am Acad Dermatol. Rapidly increasing incidence of Kaposi’s varicelliform eruption in patients with atopic dermatitis.
Eczema herpeticum is a rare but severe disseminated infection that generally occurs at sites of skin damage produced by, for example, atopic dermatitisburns, long term usage of topical steroids or eczema.
Atopic dermatitis, eczema herpeticum, herpes simplex virus. Antiviral therapy is effective in reducing morbidity and preventing complications. The lesions are painful[ 7 ] and they are often associated with fever, malaise, and regional lymphadenopathy. Detailed comparative studies of the isolated virus with that of vaccinia are recorded.
Kaposi’s varicelliform eruption complicating allergic contact dermatitis. Similar articles in PubMed. Lately, KVE has been related to the use of methotrexate and retinoids in patients with psoriasis, Erultion, and Hailey—Hailey.
All patients were treated with oral or parenteral acyclovir with a dose ranging from to mg per day until complete resolutioneeruption in 10 patients, systemic antibiotic was added. Online since 15 th March ‘ In case of doubt, the Tzanck smear allows a diagnostic approach, that is rapid and economical,[ 14 ] though not specific.
We also highlight clinical features, associations and therapeutic options.